Patient Question: Disease: Prenatal examination after thyroid surgery Description: I am in my third trimester of pregnancy and my TSH (thyroid stimulating hormone) is 0.213 (reference range 0.27-4.2mIU/L), but the rest of the indicators are normal. I would like to ask: Do I need to adjust the dosage of Eugenol now? Do I need to review my nail function every month during pregnancy? Hospital Department: Department of Obstetrics, Affiliated Hospital of Jining Medical College Treatment: Time Hospital Department: Department of Surgery, Wuhan General Hospital, Guangzhou Military Region Treatment Process: Surgery for papillary thyroid cancer, not spread, no iodine treatment, doctor requested regular review Medication: Drug name: Eugenol Dosing instructions: 2 tablets plus 1/4 tablet daily in the morning Reply from Zhang Rongjun, Department of Obstetrics, Qingdao Women’s and Children’s Hospital: Thyroid cancer that has been operated What is the goal of TSH control during pregnancy for the patient? How to give L-T4 therapy? According to ATA and ETA guidelines on DTC, serum TSH should be kept below 0.1 mIU/L in patients with uncontrolled thyroid cancer, and in patients with controlled but high-risk thyroid cancer, TSH levels should be suppressed to 0.1-0.5 mIU/L. In patients with controlled and low-risk thyroid cancer, TSH should be kept in the low normal range (0.3-1.5 mIU/L). In patients with controlled thyroid cancer and low risk thyroid cancer, TSH should be kept in the low normal range (0.3-1.5mIU/L). In patients with surgically treated thyroid cancer, the main difficulty after pregnancy is to maintain the pre-pregnancy suppression levels and prevent the development of hypothyroidism. For most patients with surgically treated thyroid cancer, the L-T4 dose is gradually increased by 9% during the first trimester, 21% during the fourth to sixth months of pregnancy, and 26% during the seventh to ninth months of pregnancy, and thyroid function should be tested as soon as pregnancy is confirmed. Thyroid function should be tested every 4 weeks and the dose of L-T4 should be adjusted. The above tests should be measured in the same laboratory to ensure the accuracy and comparability of the results. Patients should maintain established TSH suppression goals after pregnancy. Monitor serum TSH regularly, every 4 weeks until 20 weeks of gestation.