Mupirocin ointment can treat acne, because acne is mainly a skin disease caused by Propionibacterium acnes infection. While treating with topical mupirocin, you can also take oral minocycline hydrochloride capsules 50mg twice a day, mainly for acne with pustules or large cysts that are more obvious. If for acne, it is better to apply isotretinoin soft capsule orally and topical adapalene gel or benzoyl peroxide gel to treat it. For acne, in addition to the above treatment, oral Chinese herbal medicine can also be used. For damp-heat type of acne, yellow cypress capsules can be applied to treat it. For the spleen deficiency type, you can use Ginseng and Atractylodes for treatment. In addition, for large cysts with blood stasis evidence, it is better to use Rhubarb Sting Worm Pill for treatment.