Breast cancer is one of the major malignancies that threaten human health and life, with approximately one million new female breast cancer patients worldwide each year, of which at least 400,000 die from breast cancer. Surgery is the main method to cure breast cancer, but postoperative surgery may be complicated by: upper limb lymphedema, brachial plexus nerve injury, shoulder joint dysfunction, as well as patients’ uncertainty about prognosis and even anxiety and depression when facing a series of adverse reactions caused by breast loss and chemotherapy and radiotherapy. Both domestic and international studies have also affirmed the effectiveness of comprehensive rehabilitation training after breast cancer surgery in improving limb function, relieving fatigue symptoms, improving cardiopulmonary function, and improving health-related quality of life. With the development of society and the improvement of living standards, people are more and more concerned about their shape and function, as well as their quality of life and their requirements. The medical model has also developed from a purely biomedical model to a holistic medical model including biological, psychological and social factors, etc. We are not only concerned with the disease itself, but also with the organic combination of human biology and sociality, and with the function, psychology and quality of life of breast cancer patients. The joint clinic of general surgery, oncology, hospice and rehabilitation for breast cancer is the embodiment of the holistic medicine model. This multidisciplinary cooperation model can better integrate medical resources and provide more advanced medical services for patients to maximize their functional recovery. Rehabilitation of breast cancer is a cutting-edge domestic treatment concept for this disease, with different rehabilitation programs and roles for different stages of treatment. Pre-operative rehabilitation guidance can enhance communication with patients to make them understand the information related to the disease and the significance of rehabilitation and build up confidence in overcoming the disease; and guide the training and activities that can be performed and engaged in after surgery, such as the static contraction of upper limb muscles and the placement of post-operative body position, so as to prepare for post-operative rehabilitation treatment. The early stage of postoperative rehabilitation can promote venous and lymphatic reflux and reduce postoperative upper limb swelling. The second stage of rehabilitation can promote blood return and recovery of joint function, prevent muscle atrophy and joint adhesions, and reduce pain. The third stage of rehabilitation can reduce the pain and adhesions in the shoulder, promote the range of motion of the shoulder joint and the strength of the muscles around the shoulder, as well as improve the ability of daily life and build up the patient’s confidence to overcome the disease. The fourth stage of rehabilitation can improve muscle strength, cardiopulmonary function, enhance physical function and help control weight; relieve fatigue and nausea and improve sleep. In conclusion, breast cancer rehabilitation can relieve pain, promote the recovery of joint function, prevent muscle atrophy, relieve psychological pressure, build up confidence to overcome the disease and help patients recover as early as possible. Rehabilitation assessment is also a very important part of rehabilitation treatment, including assessment of joint mobility, arm circumference, pain, cardiopulmonary function and physical endurance, psychological function, ability to perform daily life and quality of life, as well as assessment of the patient’s family and the environment they live in, in order to help patients better recover their physical function and psychological rehabilitation in order to return to normal social life. The International Classification of Functioning, Disability and Health (ICF) is such a classification system that can comprehensively reflect the patient’s health status, and is currently the most advanced and popular assessment method internationally. It is one of the most authoritative and comprehensive classification systems in the world. It has been applied to the assessment of breast cancer internationally, so that it can reflect the physical, individual and social status of breast cancer patients more comprehensively, and can provide more comprehensive and accurate treatment accordingly. Therefore, many international rehabilitation centers, including Sweden, the Netherlands, Australia, the United States, the United Kingdom, South Korea, Canada, Denmark and other countries, have developed and standardized the treatment of breast cancer. And many rehabilitation departments in China have already started comprehensive treatment in this area, hoping that rehabilitation can provide breast cancer patients with comprehensive treatment that tends to the international development level and improve the effectiveness of pre-treatment.