Intestinal chemosis refers to intestinal epithelial hyperplasia, which usually requires gastric mucosal protectants and quadruple therapy if H. pylori infection is present. Intestinal chemosis may be caused by drug factors, food damage, bile reflux, and H. pylori infection. If it is only mild intestinal chemosis and no H. pylori infection occurs, oral gastric mucosal protectants, such as bismuth potassium citrate and aluminum thiosulfate, can be taken as prescribed by the doctor. However, some patients with intestinal chemosis, accompanied by Helicobacter pylori infection, if not eradicated in time, gastric cancer is likely to occur, and need to take quadruple drug therapy, i.e., a proton pump inhibitor, a bismuth, two antibiotic drugs, etc., such as omeprazole, bismuth pectin, amoxicillin, metronidazole and so on. Currently, other drugs recommended in the clinic are Morodan, Gastroflex, and so on. Allergic to the above drug components are prohibited, pregnant women, lactating women, liver and kidney insufficiency is prohibited or used with caution, if there is a significant adverse reaction after the use of the drug need to stop the drug to consult a doctor. Intestinal dysplasia need to be instructed by the doctor to use drugs not to self-medication, if the degree of intestinal dysplasia is more serious, if necessary, need to take the microscopic surgical treatment.