The skull can be called the protective shield of the brain, and its existence bears an important responsibility for the safety of life activities. After the skull defect, because the human tissue has the ability to regenerate, and the bone will keep growing, so many people will think that children with skull defects of 4 centimeters can be healed by themselves. But is this true? Children are in the stage of growth and development, tissue growth is naturally fast, so the child skull defect 4 centimeters, is it possible to heal itself? The actual situation is not satisfactory, after the child skull defect, with the growth of the body, the skull will grow along the periosteum rich area, not necessarily in the defective part of the growth of the bridging, if it is abnormal deformity growth, it is easy to fracture, for the child’s harm is also relatively large. Therefore, children’s skull defects can heal on their own is relatively rare, most of them still need to be artificially repaired. The danger of children’s skull defects is so great that parents should take a chance and think that they will grow back on their own. In most cases, the defect will need to be repaired by a neurosurgeon. Currently, most hospitals use titanium mesh material for repair, which has certain flaws and shortcomings and is therefore not ideal for skull repair. At present, our team adopts a new type of material – polyether ether ketone PEEK material for repairing skull defects, which is more stable in various properties and well avoids all kinds of problems in the postoperative period. Moreover, we have introduced the concept of aesthetics into the surgical process, which has produced good surgical results, effectively preventing temporal muscle atrophy and infection, material exposure, etc., which has been recognized by the majority of patients and their families.