Tuberculosis may cause women’s menstrual irregularities, mainly manifested as delayed menstruation, reduced menstruation, or abnormal menstrual blood color, nature, and traits, or even amenorrhea, mostly due to endocrine dysfunction. Because tuberculosis is caused by Mycobacterium tuberculosis infection, some metabolites of Mycobacterium tuberculosis can cause endocrine disorders. In addition, from the patient’s point of view, patients with the disease during the period of mental stress, poor appetite, malnutrition, poor rest, will also lead to endocrine disorders. Tuberculosis is a chronic wasting disease, patients may experience weight loss, and the central nervous system is extremely sensitive to weight change, weight loss will affect the endocrine function through the central nervous system. So all the above reasons can make the patient’s menstruation irregular and abnormal.