Iodophor can be rubbed on the nostril area, and caution is recommended for normal nasal mucosa. Iodophor has a strong bactericidal and disinfecting effect and is mainly used clinically for the disinfection treatment of skin and mucous membrane. However, nasal mucosa has olfactory zone mucosa and respiratory zone mucosa. The olfactory zone mucosa has olfactory cells distribution, and if the olfactory cells are damaged, it will lead to irreversible olfactory damage, while the respiratory zone mucosa damage will also lead to irreversible blockage of nasal mucosal cilia clearance function, causing nasal secretion retention. Iodophor is clinically useful for killing most bacteria, some viruses, some molds and protozoa. Iodophor is less irritating to skin and mucous membranes, so it can be used not only for disinfection of surgical skin incisions and intravenous and intramuscular injection sites, but also for disinfection of mucosal areas, such as the mucous membrane of the mouth and lips, the eye and genital areas.