Chemotherapy has a certain therapeutic effect for patients with advanced bowel cancer, but the extent of the effect of chemotherapy mainly depends on whether the advanced stage is accompanied by metastasis of other organs and whether the metastasis of other organs is accompanied by clinical manifestations. At the same time, it has a certain relationship with the sensitivity of each patient to chemotherapy. Some patients are very sensitive to chemotherapy and can achieve good therapeutic effect through chemotherapy, but some patients with advanced stage with metastasis may achieve insignificant therapeutic effect through chemotherapy, but it is counterproductive. Therefore, the effectiveness of chemotherapy depends on the severity of the disease and the kind of organ to which the metastasis is associated, and is also very closely related to the sensitivity of the patient to chemotherapy drugs.