Cancer pain is a major cause of suffering for cancer patients, and more than 80% of advanced cancer patients will experience moderate to severe pain. Cancer pain has various clinical manifestations and can cause serious effects on patients’ physical, psychological, social and spiritual aspects. Patients should actively participate in the treatment process of cancer pain, fully express their pain feelings, correctly assess the pain situation, and promptly let doctors know the pain level and treatment effect. (1) Mild pain (1-3 points): tolerable, sleep is not affected, and daily life is normal. (2) Moderate pain (4-6 points): unbearable, sleep is affected, analgesics are needed. (3) Severe pain (7-10 points): pain is severe, sleep is seriously disturbed, and analgesics are necessary. When the pain interferes with sleep and daily life, a doctor should be sought for treatment. The use of opioids under the guidance of a professional doctor should not worry about addiction (the addiction rate of opioids for cancer pain is around 3/10,000). It is necessary to adjust bad emotions such as pessimism, anxiety and depression, social isolation, actively participate in daily social activities, and actively participate in appropriate health exercises. Cancer pain treatment includes: surgery, radiotherapy, medication and minimally invasive interventional therapy, etc. More than 90% of cancer pain can be effectively controlled by medication. There are many kinds of analgesic drugs, which need to be selected according to the degree of pain, patient’s health condition and family economic situation. Some analgesic drugs can cause constipation, nausea and vomiting, skin itching, drowsiness, respiratory depression and other adverse reactions, which can be effectively controlled through preventive medication and symptomatic treatment.