Rheumatoid factor can be lowered through the use of glucocorticoid drugs (such as methylprednisolone) and antirheumatic drugs (such as methotrexate) under the supervision of a doctor. Rheumatoid factor is a type of autoantibody against the antigenic epitope on immunoglobulin G Fc fragment in rheumatoid arthritis serum, which can be classified into immunoglobulin M, immunoglobulin A, immunoglobulin G, immunoglobulin E. It is one of the autoantibodies related to rheumatoid arthritis, but its specificity is not high. If the rheumatoid factor is elevated due to autoimmune diseases such as rheumatoid arthritis, it needs to be treated with glucocorticoid drugs, such as methylprednisolone and prednisone acetate, etc.; and anti-rheumatic drugs, such as methotrexate and leflunomide. In addition, the immunity can be improved through daily consumption of food rich in calcium, iron and zinc, vitamins and high quality protein, such as egg white, milk, spinach, shiitake mushrooms and so on, in order to reduce the rheumatoid factor. At the same time, it is necessary to pay attention to regular exercise, ensure sufficient sleep, maintain a happy mood, and quit smoking and limiting alcohol. If the rheumatoid factor is found to be elevated, it is recommended to consult a doctor in a timely manner and follow the doctor’s instructions for standardized diagnosis and treatment, so as to avoid delaying the condition.