The main principle of the application of antihypertensive drugs is individualized treatment. No single antihypertensive drug is the most effective, and no single antihypertensive drug is suitable for all patients, and the choice is based on different blood pressure values, age and related diseases. Pulley and sartans are suitable for mild to moderate or younger patients, and for patients with combined diabetes. If the heart rate is fast, or if heart failure is combined, lorrel is appropriate. If hypertension is combined with coronary artery disease, or if the patient is older, diphenhydramine is suitable. In the case of elderly people with stubbornly high systolic blood pressure and a relatively large pulse pressure difference, it is appropriate to take diuretics in combination with other drugs for treatment. So several of the most commonly used antihypertensive drugs include angiotensin-converting enzyme inhibitors, angiotensin II receptor blockers, beta-blockers, calcium antagonists, and diuretics, to be selected according to different situations.