Whether or not the disease of upper heat and lower cold can be completely cured is mainly determined by the patient’s condition and the tolerance of the patient’s physique, and only the symptomatic treatment can receive good curative effect. The symptoms of “upper heat and lower cold” is one of the manifestations of “mixed cold and heat” (the simultaneous occurrence of cold and heat symptoms in the same patient), which is mostly caused by the lack of communication between the heart and kidney (heart fire and kidney yin deficiency, the physiological dysfunction of the heart and the kidney). It can be treated with Jiaotai Pill. The heart is in the upper jiao, belonging to fire; the kidney is in the lower jiao, belonging to water. Due to the deficiency of kidney yin, the two are out of coordination, the heart fire cannot descend to nourish the kidney yin, and the kidney yin cannot ascend to restrain the heart fire, which leads to heart-kidney disharmony, with upper heat and lower cold symptoms. You can take Jiaotai Pills. Jiaotai Pill, composed of Chuanlian Lian and Cinnamon Heart, has the effect of communicating with the Heart and Kidneys (Heart Fire descends and Kidney Water rises to restrain each other). It is mainly used for the treatment of heart fire hyperactivity, heart-kidney disharmony, symptoms such as dazed and anxious (heart beating violently, panic and restlessness) restlessness, or sleeplessness at night, mouth and tongue sores and so on. In Jiaotai Pill, Huanglian is the monarch drug, which is bitter and cold into the heart, clearing and lowering the heart fire. It is accompanied by the pungent and hot cinnamon, which warms the kidney yang. The two medicines together, so that the heart fire can be lowered, kidney yang can be restored, kidney water on the commitment, the heart and kidneys together. The specific effect varies from person to person, need to combine with their own situation, taking drugs need to be under the guidance of a doctor.