Sore eyes after insufficient sleep are related to visual fatigue, dry eye disease and glaucoma. 1. Visual fatigue: patients can’t sleep for a long time or don’t have enough sleep, resulting in excessive eye fatigue, patients may have sore eyes, swelling and other discomforts, and may also have drowsiness. 2. Dry eye: dry eye patients with tear film instability, if long-term sleep is not enough will aggravate the condition, resulting in patients with dry eyes and with obvious eye foreign body sensation. 3. Glaucoma: If patients with glaucoma use their eyes for a long time or don’t get enough sleep, the intraocular pressure may rise, resulting in patients with sore eyes, swelling and pain, loss of vision and other uncomfortable symptoms. It is recommended that patients with noticeable soreness and swelling of the eyes should consult a doctor in time to assess their condition and follow the doctor’s instructions for treatment.