Patients with acromegaly will have symptoms of aura in the early stage of the disease, usually starting with the invasion of the limbs, and may experience weakness of the hands and feet, muscle throbbing, easy fatigue, and atrophy, with the atrophy spreading upwards. An aggravation of the disease can lead to symptoms of swallowing difficulties, speech difficulties, respiratory failure, possible loss of emotional control, laughing or crying, and decreased judgment. Tachyphylaxis, also known as motor neuron disease, is associated with damage to upper and lower motor neurons. After the motor nerve cells in the central nervous system of tachypnea patients are violated, the muscles will gradually atrophy and become weak, which will further lead to paralysis and the body will look like it is frozen. Tachyphylaxis should be diagnosed as early as possible, and neuroprotective and supportive treatments should be given as soon as possible. Clinically, Lirutide is commonly used for treatment, and there is no drug that can completely block the further progression of the disease.