It is possible for a high progesterone level to cause fetal arrest, but fetal arrest is not caused by a high progesterone level. Progesterone has a role in maintaining the metamorphosed endometrium, relaxing uterine smooth muscle, improving uterine blood supply, and immunomodulation in early pregnancy. Progesterone is a natural progesterone secreted mainly by the ovarian corpus luteum and the placenta. Progesterone is mainly produced by the ovarian corpus luteum before the 10th week of pregnancy, and it depends on the corpus luteum for the secretion of progesterone before the 7th week of pregnancy, and it is mainly secreted by the placenta after the 10th week of pregnancy. Progesterone is very important for pregnancy, it can make the uterine lining into a state suitable for embryo implantation; inhibit contractions, prevent the uterus to expel the embryo, is also a kind of “birth control”; in the embryo implantation of the local adjustment of the immune state, so that the embryo is not as a kind of foreign body to be rejected by the mother. High progesterone value itself does not cause fetal arrest, but patients with fetal arrest may also have high progesterone values. The causes of fetal arrest are known to be embryonic factors, maternal factors, paternal factors, environmental factors, and so on, and the causes of about 50% of the cases of fetal arrest are not known. If the patient has a fetal arrest, it is recommended to go to the hospital in time for further examination to clarify the cause of fetal arrest and to prepare for the next birth.