Avanafil is used to treat pulmonary hypertension. Avanafil is a phosphodiesterase type 5 inhibitor that affects signaling pathways within the cell, causing the release of nitric oxide. Nitric oxide can play a role in dilating arterial blood vessels, so it can reduce the pressure in the pulmonary artery and be used to treat pulmonary arterial hypertension. However, the cause of pulmonary arterial hypertension should be clarified, and then the treatment should be directed to the cause. Avanafil can be used for the treatment of pulmonary arterial hypertension, but also has the role of the treatment of male erectile dysfunction, there are certain adverse reactions, such as headache, muscle pain and bronchitis. In addition, the combination of Avanafil and nitrate drugs may induce heart attack, so cardiac patients should use it with caution. It is recommended that it be used under the supervision of a physician to avoid delays.
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