Frostbite is a limited erythematous inflammatory disease that occurs in the terminal area after the body has been attacked by cold, and is prone to occur in wet and cold environments where the temperature is below 10°C. Frostbite occurs when the skin is stimulated by cold and the small local arteries are strongly constricted, causing skin ischemia and hypoxia, cellular damage, paralytic vasodilation and plasma exudation, resulting in edema and tissue necrosis. In humid environments, heat dissipation from the body surface is accelerated, so the incidence of frostbite is high. In addition, sweaty hands and feet and impaired local blood circulation can induce or aggravate frostbite. Frostbite usually occurs on the ends of the extremities and exposed areas, such as the fingers, back of the hands, toes, back of the feet, heels, cheeks, and ears. The lesions are limited red or purplish lumps with indistinct boundaries, low skin temperature, and an itchy sensation. The local swelling is more pronounced after heat, and blisters are likely to appear. The blistering fluid is a yellowish bloody plasma, which forms vesicles and ulcers after breaking, accompanied by pain. It often occurs in children and young women or those with poor peripheral blood circulation. The same area is prone to recurrent attacks. Appropriate physical exercise can enhance physical fitness. People who are prone to frostbite start to insist on cold water for hand and foot washing before winter, which can promote local skin circulation, eliminate microcirculatory disorders and improve the nutritional status of the skin, as well as improve the skin’s ability to adapt to changes in the external environment. Rubbing your hands and flexing your joints several times a day for a few minutes each time until the local skin is warm can prevent frostbite. You should also pay attention to proper nutrition and eat more cold-weather foods such as mutton, dog meat and chili peppers. In addition to local warmth and keeping dry, it is also important to keep the whole body warm. In addition, gloves, shoes and socks should not be too tight. If you have frostbite but have not broken, you can use vitamin E ointment, 10% camphor ointment or tincture of chili pepper topically. If you have ulcers, you can use topical Bactrim ointment, erythromycin ointment, lard and honey ointment, etc. Severe cases need to be seen in hospital.