Systemic lupus erythematosus (SLE) is a chronic systemic autoimmune disease that can involve multiple systems and organs, and develop a large number of autoantibodies. When the disease is in remission for more than half a year, there is no serious damage to the central nervous system, kidneys, or other organs, and oral prednisone is administered at a dose of <10 p.p.m. per day, it is generally safe to carry the pregnancy to term and deliver a normal fetus. Most of the immunosuppressant drugs used in the first three months of pregnancy can affect the growth and development of the fetus, so the drugs must be stopped for more than half a year before pregnancy. The drugs that can be applied to patients after pregnancy are glucocorticoids, hydroxychloroquine, and azathioprine.