Eliminating prickly heat can be treated with topical and oral medications. Prickly heat, also known as corn rash, is a common ailment in summer or hot and humid environments. Generally speaking, prickly heat can subside on its own without treatment if the skin is kept dry and cool; for severe cases, it can be treated with topical or oral medications. 1. Topical medication: Topical medication should be based on the basic principles of astringency, cooling and itching relief. Prickly heat powder or glycerite lotion can be used; if the itching is obvious, glucocorticoid drugs can be used externally, such as mometasone furoate cream, etc.; if the lesions are infected, mupirocin ointment can be used externally. 2. Oral medication: If there is obvious itching, you can take oral antihistamines such as loratadine. After prickly heat appears, wear loose and comfortable clothes to reduce contact with the affected area; keep the skin clean and dry. If there is still discomfort, it is recommended to go to a regular medical institution for consultation, and the medication needs to be used under the guidance of a doctor.