Perineal cysts may be formed due to folliculitis, Bartholin’s gland cysts or sebaceous gland cysts. Topical ointments vary for different causes, and it is recommended that patients use medication under the guidance of a doctor. Commonly used drugs are fusidic acid ointment, mupirocin ointment, mucin B ointment and so on. 1. Folliculitis: Folliculitis is formed by purulent inflammation around the mouth of the hair follicle, and it is recommended that patients use fusidic acid ointment and mupirocin ointment for treatment. 2. Bartholin’s gland cysts: Bartholin’s gland cysts usually occur in the area below the labia majora, patients can use topical antibiotic ointment, such as erythromycin ointment, mupirocin ointment, and so on. 3. Sebaceous cysts: Sebaceous cysts are bacterial infections that occur after the sebaceous ducts are blocked, and patients can be treated with compound polymyxin B ointment and erythromycin ointment. For patients with cysts in the perineum, it is recommended to go to regular hospitals for timely examination and standardized treatment under the guidance of professional doctors.