The significance of early gastric cancer screening The status quo of gastric cancer in China is high incidence rate, low early diagnosis rate and high mortality rate. The prognosis of gastric cancer is closely related to the timing of diagnosis. The 5-year survival rate of early gastric cancer patients, regardless of whether there is lymph node metastasis or not, exceeds 90% after surgery, and the 10-year survival rate of small gastric cancer and micro gastric cancer in the initial stage can reach 100%. However, the 5-year survival rate of middle and late stage gastric cancer is still less than 30%, and the treatment effect is poor and the cost is high, which brings heavy economic and psychological burden to patients’ families and society. At present, the diagnosis and treatment rate of early gastric cancer in China is less than 10%, which is much lower than 70% in Japan and 50% in Korea. Therefore, early, timely and accurate detection of gastric cancer is of great significance to reduce the mortality rate of gastric cancer. Alarm symptoms of early gastric cancer Sudden appearance of indigestion symptoms such as epigastric discomfort of unknown cause, weakness and wasting, which are more stubborn and fast progressing; prominent manifestations are rapid decrease in appetite, abdominal fullness after eating through the crumb an imperial yagyu school to protect the walk over the file stop hwan hire word pihin Q epilepsy” (19) Tombstone Hope Shang Yu Yu Yi Yuan Huang Oracle # shake pole whacking nightmare protection Chen Yun transport (19) Nightmare protection weighing (8) walk testis swallowing ξ weed The screening is conducted for more than 5 years, with symptoms such as indigestion, wasting, anemia and gastric bleeding. Screening targets for early gastric cancer According to the national conditions and epidemiology of gastric cancer in China, those who meet any of the following items 1 and 2-6 should be listed as high-risk groups for gastric cancer and are recommended to be screened: age 40 or above, male or female; people in areas with high incidence of gastric cancer; people with H.pylori infection; people with chronic atrophic gastritis, gastric ulcer, gastric polyps, post-surgical residual stomach, hypertrophic gastritis, pernicious anemia Pre-cancerous diseases such as gastric cancer; first-degree relatives of gastric cancer patients; presence of other high-risk factors for gastric cancer (high salt, pickled diet, smoking, heavy alcohol consumption, etc.). Screening methods for early gastric cancer The occurrence of gastric cancer is a long and gradual process, which provides the possibility of screening and intervention for people at high risk of gastric cancer. A new effective way to detect early gastric cancer has been explored internationally by combining serological primary screening with endoscopic diagnosis and treatment. The Department of Gastroenterology of Jiangsu Provincial People’s Hospital has introduced this international cutting-edge technology for early gastric cancer screening this year. The risk of gastric mucosal lesions can be detected in time by simply drawing 2 ml of venous blood and performing serum gastric function test. For patients with abnormal serum gastric function test, further fine gastroscopy and pathological examination can greatly improve the detection rate of early gastric cancer. Therefore, for those who have the above alarm symptoms or are at high risk, serological testing should be performed once a year, and if abnormalities are found, fine gastroscopy should be performed, so that early detection of gastric cancer and early treatment can greatly improve the survival rate and quality of life of patients.