The treatment options for lung cancer brain metastasis include brain radiotherapy combined with systemic chemotherapy, or combined with targeted drug therapy, or combined with immunotherapy, etc. Patients need to consult doctors and follow the doctor’s instruction to choose the most suitable treatment option. 1. Brain radiotherapy combined with systemic chemotherapy is generally suitable for patients with lung cancer brain metastasis who do not have gene mutation and have negative immune expression. Some patients with good physical condition can also choose the treatment plan of radiotherapy combined with anti-angiogenic targeted drugs. 2. Brain radiotherapy combined with some small molecule tyrosine kinase inhibitor targeted drugs, this plan is suitable for patients with lung cancer brain metastases who have driver gene mutations, and the targeted drugs are selected according to different mutated genes. 3. Radiotherapy combined with immunotherapy is generally suitable for patients with lung cancer brain metastases who have high immune expression.