65 years old legs, may be due to acute inflammation, hypothyroidism, anemia, cranial or spinal diseases, liver and kidney insufficiency, etc., if there is no disease after consultation, it may simply be a physiological state, such as the elderly physical weakness, emotional depression to do not want to move. 1. Acute inflammation often causes leg weakness, such as upper respiratory tract infections, gastrointestinal infections, etc. Sudden weakness, accompanied by fever or cough, diarrhea and other symptoms of patients, often acute inflammation, need to seek medical attention as soon as possible. 2. Hypothyroidism patients, often caused by fatigue, may also be due to decreased appetite, indifference, low response, etc., need to check the thyroid function. 3. Patients with anemia are prone to symptoms such as limb weakness and pallor. 4. Diseases related to the skull and spine may lead to weakness of the lower limbs, such as cerebral infarction, cerebral hemorrhage, cervical spondylosis, etc. Imaging examinations such as CT and magnetic resonance are required, and relevant treatments need to be applied according to the specific conditions of the patients. 5. Liver insufficiency, renal insufficiency patients, often cause leg weakness, blood sampling to check liver and kidney function. Therefore, if you are 65 years old and have no strength in your legs, you need to have a comprehensive evaluation, and it is recommended that you consult a hospital to clarify the cause of the disease.