With the rapid socio-economic development of China, the change of environment and diet structure and the aging of population, the incidence of tumor is increasing year by year. Due to the lack of effective early detection mechanism, most of the tumor patients are already in the middle and late stages when they seek medical treatment, which makes surgical resection difficult and some of them are limited to biopsy. The development of radiotherapy equipment and radiotherapy technology is fast, from conventional radiotherapy technology in the last century to the era of precise radiotherapy with 3DCRT, IMRT and IGRT-VMAT in this century, but the cost of radiotherapy is also growing fast, and the clinical efficacy of certain tumors is still not very satisfactory. Zhao Yuanhua, Department of Radiotherapy, Hubei Cancer Hospital The biggest complication of radiotherapy is not only radiation damage but tumor recurrence. There is a consensus that multidisciplinary comprehensive treatment such as radiotherapy, chemotherapy, biologically targeted therapy and Chinese medicine drug therapy should follow the principle of combining evidence-based medicine and humanities: avoiding treatment errors, reducing treatment shortage and reducing treatment transition. The current treatment confusion of tumor: standardized treatment? Or individualized treatment? The strategy of tumor treatment depends on the clinical and biological characteristics of tumors. A good oncologist should develop a standardized and comprehensive treatment strategy based on patient factors (age, physical condition) and tumor factors (tumor growth site, clinical stage, histological type), while taking into account patient factors (age, physical condition) to the maximum extent. Physicians’ treatment should not only let patients live long (extend overall survival), but also live well (improve patient condition, delay tumor progression, improve local control, reduce treatment toxicity, and improve quality of life). An important consideration in the strategy of individualized tumor treatment is: to “kill” or to “peacefully coexist” with cancer cells in the patient’s body? It is indeed worth thinking about! The cornerstone of individualized tumor therapy awaits advances in molecular imaging and molecular pathology, and surprises and breakthroughs should come in the near future!