Get up in the morning eyes and face edema to find out why, may be physiological, may also be pathological; physiological reasons need to adjust the lifestyle, pathologically caused by the need for targeted treatment under the guidance of a doctor, such as drug therapy. 1. Physiological: excessive intake of water or other beverages before going to bed, slow water metabolism, obstacles, swelling of the eyes and face in the morning; most of them can subside on their own, and it is recommended to drink as little water as possible before going to bed. 2. Kidney disease: the typical clinical manifestations of kidney disease are urinary abnormalities, edema, high blood pressure and other urinary symptoms; the typical manifestation is facial edema in the morning or accompanied by bilateral lower extremity depression edema. Diuretics such as furosemide need to be selected according to the patient’s condition to reduce the cardiopulmonary burden and prevent water and sodium disorders. 3. Allergy: Consider allergic reactions caused by food, pollen, dust mites, cosmetics, skin care products and so on. Oral antihistamines, such as loratadine and cetirizine, can be prescribed. Wake up in the morning eyes and face edema can not be ruled out is caused by other factors, persistent edema is obvious, we should go to the hospital in a timely manner to clarify the cause of the disease, in accordance with the doctor’s instructions standardized treatment. Drugs need to follow the doctor’s instructions to use, not blindly self-medication.