Skin spots during menopause can be seen in melasma and age spots, and the treatment mainly includes medication, physical therapy and surgery. 1. Melasma: mainly manifested as facial pigmentation spots, mostly seen in middle-aged and old-aged women, the treatment includes topical medication, oral medication and laser treatment. (1) Topical medication: Topical depigmenting agents (2% hydroquinone cream) and antioxidant medication (retinoic acid cream) can help improve the symptoms of melasma. (2) Oral medication: Take some antioxidant medications orally to improve skin quality, such as vitamin C tablets and vitamin E gel pills. (3) Laser treatment: Using heat energy of laser to destroy pigmentation, which is more commonly used. 2. Age spots: Age spots, also known as seborrheic keratosis, are mainly flat papules or plaques slightly protruding from the surface of the skin, and their treatment mainly includes topical medication, laser, freezing and surgical treatment. (1) Drug treatment: local topical application of drugs that have the ability to dissolve keratin, such as retinoic acid cream, salicylic acid cream and so on. (2) Laser treatment: use the heat energy of laser to directly cause burns to age spots in order to remove age spots. (3) Cryotherapy: Using the extremely low temperature of liquid nitrogen to cause frostbite to local tissues to remove age spots. (4) Surgical treatment: Using spoon scraping method or direct surgical excision can remove age spots quickly. After the appearance of skin spots in menopause, it is recommended to take standardized treatment under the guidance of doctors, and do not use medication on your own.