Spots on both sides of the nose are commonly caused by chloasma, which need to be removed by medication or photoelectric treatment on the basis of sun protection. 1. Medication: Hydroquinone and its glycoside derivatives are common, which are the first-line drugs for melasma treatment, in addition to azelaic acid, retinoic acid, tranexamic acid and other topical drugs, and can also be combined with vitamin C, vitamin E, glutathione and other systemic drugs. The above drugs should be used according to the doctor’s instructions. 2. Photoelectricity treatment: mainly includes laser treatment and intense pulsed light treatment, but need to pay attention to the occurrence of inflammatory reactions, scar formation and other adverse reactions. It is recommended that patients go to regular hospitals for consultation and treatment, and choose the appropriate treatment method under the guidance of professional doctors, so as not to cause bodily harm.