The potential risk for high-risk children is brain injury. After the occurrence of brain injury, if not diagnosed early and treated early, it may lead to pediatric central coordination dysfunction, mental retardation, epilepsy, behavioral and emotional abnormalities, sensory impairment, and even cerebral palsy that leads to abnormal motor posture, physical and intellectual disability. I. Early manifestations of brain injury in infants and young children 1, easily startled, agitated or drowsy, frequent crying, sleep disturbance or sleepy “good boy”. 2.Pleasant exertion, jerking, red face or general flabbiness, weakness, or jaw trembling, limb trembling. 3, feeding difficulties, frequent vomiting, anorexia. Repeated constipation (stool once every 3-10 days, knotted and dry stool). 4.Sweating: sweating all over the body during the day and the second half of the night, even sweating profusely. 5.When changing diapers, it is difficult to separate the thighs to the outside or the angle of separation is too large. When taking a bath, the child makes a fist with both hands and it is difficult to break it, and there is a fear of bathing and a sense of panic. Early manifestations of brain injury in infants and young children 1, infants like to jerk, head back, arms and legs often straighten or bend, as if “very strong”; or flaccid and weak; 2, feeding difficulties, weight does not increase; difficulty in sleeping, night crying, easy to frighten or excessively quiet; 3, after the full moon, the head always tilted back; can not erect the head for 15 seconds. 4.Can’t hold the head up steadily after 3 months of age; 5.Poor reflection of sound, not looking after people or objects, not smiling. 6.4 months old still clenches fist, does not release hand, thumb inward; 7.5 months old can not reach out to grasp objects; forearm can not support body in prone position; 8.6 months old pointed foot when holding stand; poor response to own name; 9.7 months old can not unconsciously pronounce “Dad”, “Mom “10.8 months old cannot sit alone; 11.Mouth and lips, jaw and or hands and feet shake frequently; 12.After 1.5 years old, cannot walk alone.