Numbness and weakness of limbs can be divided into physiological and pathological causes, and pathological causes include endocrine diseases, orthopedic diseases and neurological diseases. 1. Physiological reasons: if the environment is too cold, the blood circulation will be slow, resulting in numbness and weakness of the limbs, which is a normal physiological phenomenon, wearing cold clothing can be restored to normal, without additional special treatment. 2. Pathological causes: diabetes and other endocrine diseases can cause numbness and weakness of the limbs, because this disease will lead to peripheral nerve damage; some orthopedic diseases can also lead to this symptom because of the compression of the nerve root, such as cervical spondylosis and lumbar disc herniation, etc.; cerebral infarction, spondylitis and neuritis and other neurological disorders can be due to the compression of the nerves or inflammation leading to damage of the nerves, which can lead to this symptom. Numbness and weakness of the limbs, especially if it is not relieved for a long time or if it recurs, you should consult a doctor in a timely manner to identify the cause and carry out targeted treatment under the guidance of the doctor.