Interventional therapy is a treatment modality that combines simple diagnostic radiology and precise minimally invasive treatment techniques guided by imaging methods, which can complete the previous drastic surgery through a small hole on the body surface, opening up new avenues for diagnosis and treatment of diseases. Interventional treatment is easy and safe to operate, fast and effective, with little damage, few comorbidities, low cost, quick recovery and many other advantages, showing a broad prospect. It has won widespread attention and application in the medical community at home and abroad, and is welcomed by the majority of patients. Some diseases that were previously considered incurable or intractable are likely to have unexpected effects after treatment by interventional means. At present, most people know little about the subject of interventional therapy treatment. The following is my introduction to the interventional treatment of some common diseases. Radiofrequency ablation–a new tool for minimally invasive tumor treatment Tumor radiofrequency ablation therapy is the most advanced minimally invasive tumor resection treatment method that kills more tumors but damages the organism less. This technology is based on the characteristic that tumor cells are less tolerant to heat than normal cells, and applies radiofrequency thermal effect to heat tumor tissue to about 100℃ to cause coagulative necrosis of cancer cells and achieve the purpose of eliminating tumor. The whole process of radiofrequency ablation treatment is carried out under the observation and guidance of imaging equipment, which is precise in treatment targeting, clear in scope and easy to control, and will not cause damage to the surrounding normal tissues due to high temperature. After the implementation of radiofrequency ablation, a coagulation necrosis zone with clear and spherical boundary is formed around the ablation electrode, and the tumor tissue covered by this zone is destroyed and inactivated. The coagulated necrotic tissues are partially absorbed by the body, and these necrotic tissues have tumor seedling effect due to the change of their cellular immune phenotype, and henceforth play a special anti-cancer role to strengthen the immune function of patients and further improve the therapeutic effect. For tumors below 3 cm in diameter, a single RF ablation treatment can completely eliminate the local tumor and achieve the same effect as surgical resection; for tumors larger than 3 cm, single- or multi-point superimposed RF ablation treatment can be used, or arterial embolization of the tumor can be performed first to make part of the tumor necrotic, and then single- or multi-point superimposed RF ablation treatment can be used to finally burn the whole tumor to death. Radiofrequency ablation can be used for the treatment of benign and malignant solid tumors of human organs. At present, it is more clinically used for: liver cancer, lung cancer, kidney cancer, metastatic tumors of liver and chest. For patients with the above mentioned primary or metastatic advanced tumors that cannot be surgically removed, and solid tumors that cannot bear radiotherapy and chemotherapy, they can receive radiofrequency ablation treatment. The biggest advantage of radiofrequency ablation is that the trauma is very small, with only a needle eye of about 1mm, and there is no obvious discomfort after the operation. Since the Department of Interventional Medicine of the Second Hospital of Soochow University introduced the latest generation of radiofrequency ablation treatment technology for tumors from the United States four years ago, it has successfully carried out more than 300 procedures, completely eliminating cancer lesions in many patients’ bodies and enabling them to return to healthy work and life. Treatment of jaundice – improving patients’ quality of life Malignant obstructive jaundice is a disease caused by various malignant tumors of the pancreaticobiliary system, which is due to tumor compression of bile duct narrowing or occlusion in different parts. The interventional approach has become a common clinical treatment for malignant obstructive jaundice with its advantages of easy operation, minimal trauma, few complications and high success rate. Although it cannot cure the primary disease, it can effectively control the symptoms of jaundice and improve the patient’s quality of life. Once malignant obstructive jaundice is present all are in the middle and advanced stages of the tumor, and if patients are not treated in time, they will die in a short period of time due to liver failure or hepatorenal syndrome. Percutaneous transhepatic biliary drainage + endobiliary stent implantation is the most commonly used interventional treatment, which is performed by puncturing a rice-sized hole in the patient’s abdomen with a needle, entering the bile duct through this hole, and placing a metal stent to expand the compressed bile duct. We have received high praise from patients for less pain and higher efficacy. They have successfully performed this surgery on a 98-year-old patient, the oldest reported patient in China to have undergone this type of surgery. Through long-term exploration and technical innovation, we are now able to treat extremely complex diseases such as malignant obstruction of the hilar bile duct, multi-branch biliary obstruction, and restenosis after biliary stenting by interventional means. Abdominal plexus destruction – a fine needle to cure cancer pain Cancer pain refers to pain caused by cancer, cancer-related lesions and anti-cancer treatment. Pain is one of the most common symptoms of cancer patients. The incidence of pain in advanced cancer patients is 60% to 90%, and 1/3 of them have severe pain, which is the most fearful and painful symptom for patients. The interventional treatment of abdominal plexus disruption is determined by CT scan, then a hair-thin puncture needle is inserted into the abdomen percutaneously, avoiding important organs and inserting into the plexus only 1-2mm in front of the aorta, injecting a small amount of drugs to make sure the patient has no adverse reaction, and then starting the disruption treatment by injecting anhydrous alcohol through the needle tip. The whole process of treatment is carried out under the surveillance of CT scan, which requires a high level of the surgeon’s CT reading skills and interventional puncture skills. Pharmacological analgesia is another means of treating cancer pain. Although effective for most patients, it is costly and all of them have side effects such as nausea, vomiting, constipation and dizziness. In contrast, the new technique of abdominal plexus disruption can fundamentally cut off the nociceptive transmission, so that patients no longer feel pain, and the precise guidance of CT ensures the safety of this minimally invasive procedure, which is an excellent treatment method for advanced cancer pain patients to reduce pain and improve their quality of life.