The drugs that can be used for perianal inflammation include topical drugs, local injections and other drugs, and which drug is preferred should be decided according to the specific symptoms of the patient. 1. Topical drugs: mainly including zinc oxide, hormone cream, mainly used for acute perianal inflammation period of perianal redness and swelling or when there is local oozing. In addition, it also includes erythromycin and miconazole nitrate, which can be used when the perianal infection leads to systemic symptoms or when a specific bacterial or fungal infection is identified. 2. Local injection: you can use lidocaine or bupivacaine and so on, mainly applicable to the emergence of local itching, redness, swelling, pain when used. If perianal inflammation occurs, you should consult a doctor in time, and the relevant drugs should be used under the guidance of the doctor.