Eat progesterone stop 1 day to menstruation, if there are no other symptoms, such as abdominal pain, fever, etc., and menstruation in the end of the normal cycle, is a normal phenomenon, if the amount of bleeding is different from the normal amount of menstruation, it is more likely to be 1 day after stopping the drug is more likely to be vaginal bleeding irregularly, if accompanied by symptoms of abdominal pain, can be considered as a preterm miscarriage may be required to go to the hospital to be examined. Causes and treatment 1, normal situation: progesterone has the effect of transforming the endometrium from the reproductive phase to the secretory phase, after taking progesterone, it will stimulate the endometrium to undergo necrosis and exfoliation in the secretory phase, which will cause menstrual bleeding. Generally, menstruation will come in 3-7 days after stopping progesterone, but since the thickness of the endometrium is different for each woman and the sensitivity to progesterone is different, the exact time of menstruation after stopping the medication varies. Therefore, as long as the amount of menstruation is normal, no abdominal pain, fever and other uncomfortable symptoms, take progesterone to stop the drug 1 day to menstruation is also a normal phenomenon, no special treatment, close observation of the body can be; 2, preeclampsia: luteinizing period and during the period of sexual intercourse, and no contraceptive measures, the amount of bleeding is different from the normal amount of menstruation, and accompanied by symptoms of abdominal pain, can be considered as a preeclampsia may be. It is necessary to go to the hospital in time for blood HCG and ultrasound examination. If the diagnosis of preeclampsia is confirmed, you need to actively carry out the treatment of birth control, if the birth control is ineffective, if necessary, under the guidance of the doctor to terminate the pregnancy. Precautions to take progesterone need to be under the guidance of a doctor to use medication, do not increase or decrease the drug without authorization, so as not to cause harm to the body, before taking the drug is recommended to check the blood HCG to clarify whether the pregnancy.