In general serum osteopontin is twice as high as the upper limit of normal value, suggesting a possible risk of neoplastic lesions.
Serum osteopontin is a kind of epithelial cell scaffolding protein that constitutes the cytoskeleton of human body, and there are more than 20 kinds of them, among which the ones that are abundantly expressed in the tumor cells are CYK19, CUL19, etc. CY211 osteopontin is an important indicator for the diagnosis of lung cancer, and the normal range of it is less than 3.3 ng/mI. It is expressed in the serum of patients with lung cancer in large quantities, which is clinically significant for the diagnosis, treatment and prognosis.
Generally speaking, serum osteopontin is higher than twice the upper limit of normal value, suggesting that there may be a risk of tumorigenic lesions. However, high serum osteoprotegerin is not always cancerous, but can also be caused by inflammation.
Therefore, patients with high serum osteopontin should go to the hospital for further examination, combining with the patient’s symptoms, signs and other tests, to make a clear diagnosis and then carry out further treatment.