Whether HPV positive is serious or not is judged according to the patient’s disease, the patient may have no disease or suffer from flat warts, condyloma acuminatum, cervical cancer and other diseases. 1. No disease: if the patient resistance is high, can clear the human papillomavirus by themselves, usually do not need treatment, so it is not serious. 2. flat warts: is caused by the human papilloma virus infection of the skin mucosa, lesions are generally slightly elevated flat papules, no discomfort symptoms, available topical drugs for treatment, if the topical drugs are ineffective, you can perform wart excision surgery. The actual fact is that it’s not a very serious problem. 3. acromegaly: acromegaly is a common sexually transmitted disease caused by human papillomavirus infection, manifested as papules around the genitals, keratinized plaques, papillae or cauliflower pattern superfluous organisms, has a strong contagious, easy to recurring characteristics. Therefore, this situation is more serious. 4. Cervical cancer: persistent infection of human papilloma virus may cause cervical intraepithelial neoplasia, cervical cancer, etc. Cervical cancer may still recur after treatment, and it also affects life expectancy. Therefore, it is very serious. If you find HPV positive, you should go to the hospital in time to check the cause of the disease and treat the symptoms according to different causes to avoid delaying the disease.