Exploring objects with the mouth (orofacial exploration disorder) is seen in Alzheimer’s disease dementia. Alzheimer’s disease dementia used to be referred to as progeria for those with onset before the age of 65 and senile dementia for those with onset after the age of 65. The differential diagnosis of exploring objects by mouth: 1, organic brain mental disorder Organic psychosis caused by direct damage to brain tissue, such as: brain trauma, brain hemorrhage, intracranial tumors and other factors. 2, schizophrenia is one of the more common heavy psychosis, mostly in young adults can be divided into paranoid type, youth type, stress type, simple type, etc. The common symptoms are: mental trance, mania, hallucinations and delusions, excitement and agitation, hitting and destroying things, depression and paranoia, etc. The course of the disease is prolonged, the patient and family members suffer a lot. 3, obsessive-compulsive disorder obsessive-compulsive neurosis is a neurosis, a kind of anxiety disorder. Patients suffering from this disease are always plagued by a compulsive thinking. Patients repeatedly have compulsive ideas and compulsive behavior in their lives. The patient has intact self-awareness and knows that this is unnecessary and even painful, but cannot get rid of it. Most of the objects explored by mouth have a poor prognosis, with some patients gradually improving their symptoms as the primary illness improves. Carbamazepine, haloperidol, tranquilizers, and cholinergic drugs are effective for behavioral abnormalities caused by KBS.