The causes of elevated estradiol during menopause are physiologic and pathologic. Physiological causes may include improper diet and mental stress, while pathological causes include endocrine diseases and tumors. 1. Physiological reasons: If women consume too much hormone-containing food such as beans during menopause, or if they are under constant stress, estradiol may rise. It is recommended to adjust dietary habits, adjust work and rest, and relax the mood, and estradiol will slowly fall under the body’s self-regulation. 2. Pathological reasons: Generally speaking, estradiol will not increase during menopause, but if it does, it may be due to pathological changes in the endocrine system or tumors in the female reproductive system, leading to endocrine disorders, which may result in increased estradiol. It is recommended to go to the hospital for further examination to clarify the cause of the disease and to determine the next step of treatment under the guidance of a professional doctor.