Sore legs after standing for a long time are generally considered to be caused by muscle fatigue, lumbar disc herniation and pear-shaped muscle syndrome, meniscus injury, varicose veins and other diseases, which need to be treated with rest, medication and surgery for different diseases. 1. Muscle fatigue: Because of the work, it is necessary to stand for a long time, due to the poor blood return of the lower limbs, the pressure of the blood vessels is increasing, blood stagnation, and a light or heavy discomfort occurs. It can be relieved quickly by taking rest and choosing suitable shoes. 2. Lumbar disc herniation and pear-shaped muscle syndrome: leg pain after standing for a long time may be the sciatic nerve function is impaired performance, the common cause of lumbar disc herniation, pear-shaped muscle syndrome. Lumbar disc herniation and pear-shaped muscle hypertrophy will mechanically compress the sciatic nerve and cause leg pain. Traction and minimally invasive surgery can be performed. Piriformis syndrome can be treated with surgical release. 3. Meniscus injury: meniscus injury patients can cause standing for a long time to cause pain in the knee joint and the surrounding tissues. Braking is needed, and arthroscopic surgery can be performed to close the meniscus if the condition is serious. 4. Varicose veins: Varicose veins in the lower limbs can cause blood reflux obstacles and leg pain after standing for a long time. You need to wear compression stockings, and in serious conditions, surgery can be performed. The above drugs need to be used under the guidance of a physician. If the pain is not relieved for a long time, you need to go to the hospital in time.