High aminotransferase is considered to be a high possibility of liver disease, and liver function, liver ultrasound, abdominal CT, hepatitis kit, and liver puncture can be improved to make a clear diagnosis. Commonly used aminotransferases mainly include glutamine aminotransferase and aspartate aminotransferase, both of which are found in high levels in the liver. When the liver is damaged, aminotransferases are elevated, so liver disease is considered to be a high possibility. A complete set of liver function can be perfected, which can monitor the dynamic changes of transaminases and elevated bilirubin to assess liver function; ultrasound of the liver can find out whether there are organic lesions in the liver, such as hepatocellular carcinoma, cirrhosis, and hepatic cysts, etc.; and abdominal CT can find out the lesions in the liver and the surrounding tissues, such as extrahepatic choledocholithiasis and intrahepatic choledochal stones. Hepatitis complete set can find various viral hepatitis conditions, such as hepatitis A, hepatitis B, hepatitis C, etc., which helps to clarify the diagnosis. Liver puncture can identify the type of pathological changes in the liver and help to confirm the diagnosis of the disease. In case of elevated transaminases, it is recommended to consult a doctor in time for reasonable and standardized treatment under the guidance of the doctor.