Patients with endometriosis often ask, “Can my disease be cured? It is very reluctant to answer straightforwardly, but very unfortunately, it still has to be said that endometriosis is currently classified as a chronic disease that is not curable! Being a chronic disease, we would have to live with it for the rest of our lives. So, I say that in the face of endometriosis, we have to treat it as a “friend”. It is just a “bad friend” that we can’t choose on our own and can’t get rid of. It is easy to get along with a good friend, but difficult to get along with a bad friend. Since we have to be with it, we should be with it well, or at least not let this “bad friend” spoil our mood, right? So how do we try to make peace with it? Whether it’s now or in the past, whether it’s medication or surgery, our overall goal is to relieve pain, increase the chances of conception, and prevent recurrence and malignancy. I. Pain relief There are many ways to relieve pain, the first one we consider is painkillers, our common clinical painkillers are indomethacin, aspirin, dihydrocodeine, morphine, etc. These painkillers have their own advantages and disadvantages, the first two have no addictive properties, but the gastrointestinal side effects are heavy, the latter two have addictive properties, but the gastrointestinal side effects are light. Another class of drugs is hormonal drugs, such as progestin, anti-progestin drugs, gonadotropin-releasing hormone agonists, etc., which also have analgesic effects. There are also Chinese herbal medicines with good pain relief effects, in which the active ingredients are similar to those of Western medicines. Since there are many subjective factors and individual differences in pain, patients can choose pain relievers that are suitable for them. At present, the understanding of somatic and psychological reactions caused by pain has been improved compared with the past, and the application of analgesics is not as narrow as it was in the past. The primary principle of pain relief is to not let pain interfere with the normal life and work of the person in pain. The greatest side effect of pain relief should be that the pain sufferer ignores the existence of the disease after the pain is relieved, leading to the aggravation of the disease without realizing it. Pain relief has nothing to do with the relief of the disease itself, and one should never think that when the pain disappears, this disease is gone. Second, to increase the chance of conception Measures to increase the chance of conception mainly start from restoring the anatomical structure, reducing the presence of lesions, adjusting the endocrine imbalance, and assisting conception. The first two require surgical treatment and the latter two require medication. There is no definite method for this type of surgery, and the main purpose of surgery is to restore as much as possible the anatomical structure destroyed by endometriosis to its natural state before the disease, and to remove as many lesions as possible to avoid damage to important organs. If too many lesions are removed, the possibility of damaging the vital organs increases, and if large areas are damaged, the restored anatomy will be damaged again by adhesions. Therefore, the earlier this surgery is performed, the better the results, and laparoscopic surgery is preferred. In addition, part of this disease is accompanied by endocrine disorders, which are also a factor in infertility and require medication to adjust and, if necessary, the use of assisted reproduction techniques to help conception. Pregnancy itself cannot change the outcome of the disease, but during pregnancy, due to the action of progesterone, the ectopic endometrium undergoes methylation as well as the in situ endometrium, thus making the disease relatively quiescent, and during lactation, due to the elevated prolactin, ovarian hormones are suppressed, which also inhibits the ectopic endometrium, thus delaying the development of the disease. The disease is not carried away by the child as rumored. The recurrence rate of this disease is very high, almost 100%, and the non-recurrence is just not long enough, the good thing is that the malignancy rate is extremely low, usually not more than 1%. Because the etiology is not exact, the reasons for preventing recurrence are not component. However, clinical phenomena tell us that the disease will worsen after abortion, making the disease manifest obviously, so we should avoid accidental pregnancy; in addition, estrogen can promote the development of the disease, if you need to take estrogen needs to be applied under the guidance of the doctor. According to the theory of Chinese medicine, it is also not suitable for cold and spicy diet. In short, regular review, early detection, early diagnosis and early treatment are the best strategies to effectively control the recurrence and malignancy of the disease.