Some pancreatic surgeries can be performed without frozen section, and some of them need to be sectioned for pathologic examination to clarify the diagnosis, i.e., to guide the postoperative treatment. Surgical treatment of pancreas includes acute pancreatitis, chronic pancreatitis, pancreatic cancer, pancreatic neuroendocrine tumors, pancreatic cystic diseases, etc. 1. When acute pancreatitis is combined with other acute abdominal diseases, common bile duct obstruction, biliary tract infection, intestinal perforation, and secondary infection of pancreatic necrotic tissues, it is feasible to perform pancreatic surgery to remove necrotic pancreatic tissues, and it is not possible to do frozen section. 2. If chronic pancreatitis is combined with intestinal obstruction or cancer is suspected, pancreatic surgery is needed, and frozen section is needed to determine whether it is cancer or cancer. 3. Pancreatic cancer and pancreatic neuroendocrine tumor, after pancreatic surgery, need to routinely perform frozen section to confirm the diagnosis and determine the pathologic typing, and guide the postoperative treatment plan. 4. Pancreatic cystic diseases include pancreatic pseudocysts and pancreatic cystic tumors, when pancreatic surgery is performed, frozen section should be performed to determine the nature of the cysts and guide the later treatment. Whether to do frozen pathology section for pancreatic surgery depends on the condition of the patient, and it is recommended to follow the doctor’s advice and reasonable and standardized treatment.