Dr. Cheng, in the last two months I found a soybean-sized growth on the top of my child’s head, what is it?” “How old is the child? Does it hurt? Does it itch?” “Six years old. It doesn’t hurt or itch.” The history was simple: six years old, yellowish growths on the top of the head, found for two months, painless and itchy. The history was simple, but very characteristic. Combined with the pictures, the diagnosis was “juvenile yellow granuloma”. However, it was necessary to differentiate it from a sebaceous nevus. Juvenile yellow granuloma, also known as nevoid yellow endothelial cell tumor, is it scary to hear the word “tumor”? Don’t worry, it is common in young children and its cause is unknown. It may be related to infection or physical stimulation, or autoimmune disease. Juvenile yellow granuloma is relatively rare, usually round, translucent, red or yellowish, the surface may have capillary dilatation, often without symptoms. Systemic juvenile yellow granuloma is even rarer. When the above symptoms are detected, it is recommended to go to the hospital for examination to clarify whether there is any other organ involvement, such as: brain, eyes, liver, lungs, bones, kidneys, colon, and so on. If there is no systemic damage, no treatment may be needed as the disease is self-limiting and most of them will subside by the age of 3-6 years. Electrocoagulation, laser, cryotherapy or surgery may be an option for those that do not subside.