White spots on the hands may be due to vitiligo, acanthosis naevus and other conditions. 1. Vitiligo is a common acquired pigment loss skin and mucous membrane disease, and its main symptom is usually manifested as white hair or white spots, which can occur in all parts of the body, so white spots on the hands may be due to vitiligo. 2. The non-pigmented nevus is a congenital, rare limited pigment loss spots, its main features have pale white, different sizes, limited hypopigmentation spots, usually in the lower abdomen, trunk and other parts of the occurrence. White spots on the hands can also be seen in senile leukoplakia, anemia nevus, etc., should go to the hospital in time, symptomatic treatment.