A sprained thumb joint should be rested first, and if necessary, the metacarpophalangeal and interphalangeal joints of the thumb can be fixed with a brace or cast. Adequate rest of the thumb joint can promote the self-repair of the joint. Secondly, the swollen soft tissue of the thumb joint can be iced within 24 hours for 10-20 minutes at an interval of 1-2 hours, and hot compresses can be applied after 48 hours. At the same time, anti-inflammatory and analgesic medications are applied to relieve the pain and aseptic inflammation caused by the thumb injury. Commonly used drugs include oral celecoxib capsules, etoricoxib tablets, fotarolimus tablets, dolichol capsules, or topical ointments, such as fotarolimus ointment, wound treatment ointment, etc.