Adapalene gel and isotretinoin gel can treat common acne, but they differ in their use and adverse effects.
Both Adapalene Gel and Isotretinoin Gel belong to the class of retinoids, the former being the third generation of retinoids and the latter being the first generation of retinoids. Both retinoids have the ability to regulate cellular metabolism and the rate of exfoliation of stratum corneum cells, thereby removing acne and inhibiting acne formation, as well as inhibiting localized inflammation and reducing the production of acne marks and scars.
However, they differ in their therapeutic focus and irritation.
1. Adapalene Gel is mainly composed of adapalene, clinically applicable to the skin treatment of acne vulgaris with pimples, papules and pustules as the main manifestation of acne, can reduce the inflammatory reaction, the most important feature is mild and less irritation.
2. isotretinoin gel main ingredients include isotretinoin, this drug is mainly used for mild and moderate acne vulgaris, but for severe closed acne effect is better, the most prominent role is to inhibit sebum secretion, at the same time can be exfoliating pore size, can also reduce the inflammatory response to prevent pimples, but irritation is stronger than adapalene.
Adverse effects of isotretinoin gel are obvious, manifested by the occurrence of erythema, swelling, flaking, crusting, pigmentation or hypopigmentation, so it is generally in the case of conventional treatment is ineffective before considering the use.
The use of medication should follow the doctor’s instructions, it is best not to use drugs blindly, but also need to keep the skin clean and hygienic.