Myocardial fibers have a spiral pathway

  The role of the heart is to promote blood flow, provide sufficient blood flow to organs and tissues to supply oxygen and various nutrients, and take away the end products of metabolism (such as carbon dioxide, urea and uric acid, etc.) so that cells maintain normal metabolism and function. For example, in a quiet state, the heart beats about 70 times a minute and pumps 70 ml of blood each time, so it pumps about 5 liters of blood per minute. The heart is indeed a miraculous human organ.  In 1628, Harvey (1578-1657), an English physician, published a book entitled “A Treatise on the Movement of the Heart and Blood”. Based on anatomical observations and experiments on 40 different animals, he concluded that blood circulates in the body without ceasing. He found that the right and left parts of the heart do not contract simultaneously, and that the valves at the atrioventricular orifices of the right and left atria and left and right ventricles are one-way valves, as are the venous valves in the veins. Apparently, blood is pushed out of the heart, flows along the arteries throughout the body, and then follows the veins back to the heart, and the valves serve to prevent backflow of blood. Harvey’s discovery has been hailed as one of the ten greatest scientific discoveries of mankind, yet there are still unanswered questions about the circulatory system. The heart, the engine of the human body, whose contraction and diastole provide a constant source of power for blood to circulate through the blood vessels, has been thought for many years to be a homogeneous muscular organ, and it is not well understood what its internal anatomy is and how it works.  The existence of spiral myocardial fibers was first recognized in humans in 1660, when Lower first documented that the myocardial fibers in the apical part of the heart traveled in a vortex-like pattern, with the fibers moving from the outside toward the center in a clockwise direction and from the center toward the periphery in a counterclockwise direction. This spiral myocardial fiber course also attracted the attention of surgeons, who found that the heart was not the homogeneous muscle-like organ it was thought to be, but rather that there was a complex winding spiral of myocardial fibers that differed internally and externally, and that anatomists wanted to learn more about this strange structure, but struggled to figure out where the spiral began and ended. It was not until the last century that Dr. Torrent-Guasp finally unraveled this miraculous knot by completely unraveling the entire spiral of the heart by manual dissection and discovered that the complex myocardial spiral was formed by a single myocardial ribbon structure that was coiled twice. When asked how he unraveled this complex structure, Dr. Torrent-Gausp said that it was germline development that inspired him, because the developmental process of an individual actually repeats the evolutionary process of the germline. In turn, the heart development process can be understood indirectly by studying the evolution of the heart from lower to higher organisms. The heart of a worm, an ancient organism more than 1 billion years old, is a simple striated structure (if it can be considered a heart), and 400 million years ago, when fish appeared, it already had a single-chambered pump structure in its heart, and in the hearts of amphibians and reptiles, which appeared 200 million years ago, a formed atrial and ventricular chamber structure can be observed, but the atrial septum and septum separating the atria and ventricles still communication remains. In humans, which appeared about 100,000 years ago, the septum and septum are intact, meaning that the human heart has formed separate left and right heart structures. Let us look again at the development of the heart in a single human individual: at day 20 of life, the human heart is similar to that of a billion year old worm, a simple band structure; by day 25, the venous and arterial systems are completely separated, as well as a single pump structure is formed, a structure very similar to the heart structure of fish; by day 30, the defective band At day 30, the atrial septum and ventricular septum are formed, and the heart at this time is like the heart of amphibians and reptiles; at day 50, the atrial septal defect and ventricular septal defect are closed, and the development of the human heart is complete. This means that the human heart repeats a billion years of germline evolution during its 50-day developmental period. In accordance with this rationale, Dr. Torrent-Gausp untwisted the intricate myofibers of the heart with his bare hands, first separating the aorta and pulmonary artery, followed by the outer wall of the right ventricle, then the transverse myofibers at the base of the heart covering the surface of the apical spiral, then freeing the aorta from the left ventricle, separating the ascending and descending branches of the apical spiral, and opening the apical spiral in the direction of the myofibers. After the apical spiral is opened in the direction of the myocardial fibers, the whole heart becomes a myocardial strip, and if this strip is folded in the opposite order, it can be restored to a complete heart structure.  Why does this complex myocardial spiral structure exist in the heart? The answer is to facilitate twisting, as in a waltz. Indeed, the heart doesn’t contract and expand like a balloon as we think, but twists and turns like a dance. The ejection process process is a spiral tightening process, and the diastole is also an active untwisting process that produces a suction effect to draw blood into the heart. This phenomenon can be clearly seen in cardiac surgery, when the heart is fully exposed, when looking from the apical to the fundus direction it can be observed that when the heart is contracted, the apical part of the heart rotates in a clockwise direction, while the bottom of the heart rotates in a counterclockwise direction, and at the same time the heart becomes shorter, ejecting blood into the aorta; the process during diastole is exactly the opposite of that during contraction, the myocardium actively deconvolves, the apical part of the heart rotates in a counterclockwise direction , the base of the heart rotates in a clockwise direction, and the heart becomes longer, creating a suction force that draws blood from the left atrium into the left ventricle. In addition to visualizing the twisting of the heart intraoperatively, many scholars have used modern medical imaging procedures to reconstruct the heart in three dimensions, so that the interrelationship of the different parts of the heart can be clearly seen under fluoroscopy as it moves. An animation of the heart spiral can be seen.  Because the heart is an organ composed almost entirely of muscle tissue, there is no rigid bony-iliac structure that can serve as a fulcrum or support for muscle contraction, and the spiral structure of the myocardial fibers and their special torsional motion can achieve high mechanical efficiency. In the normal heart, due to the spiral winding of myocardial fibers, the contraction of 15% of myocardial fibers may produce an ejection fraction of 60%, whereas if the myocardial fibers are assumed to be wound in a horizontal circumferential pattern, the contraction of 15% of myocardial fibers can only produce an ejection fraction of approximately 30%. When the disease reaches the stage of cardiac failure under the action of certain pathological factors, the heart tends to enlarge spherically, at which time the course of myocardial fibers changes from a vertical crossover to a near horizontal state, and the efficiency of myocardial contraction decreases, resulting in a vicious circle. In this sense, the efficient structure of the myocardial spiral is an important guarantee for the uninterrupted work of the heart from the beginning to the end of the individual life cycle for decades.  In fact, spiral structures are not only found in the heart, but also in many structures in the human body, such as DNA, which is a double helix, human fingerprints, human hair, etc. If we look at the biological world, spiral structures are even more common, such as the horns of sheep, the shell of snails, the stamens of daisies, etc. In real life, if you look carefully, you will find spiral structures everywhere, from galaxies to the ion flow in cells, and all kinds of decorative patterns can be seen in daily life. The spiral structure is the code of life, the curve of nature, and the spiral movement is the dance of life, the rhythm of nature.