In babies with physiological murmurs, no abnormalities in heart size, structure, hemodynamics and cardiac function are seen on cardiac ultrasound, which means they are normal healthy children and can routinely undergo vaccinations, preschool education and other activities; the prognosis of babies with functional murmurs is related to the original disease. If the murmur is pathological, auxiliary tests should be performed as early as possible to clarify the diagnosis. The finer arterioles, small atrial and ventricular septal defects, and unclosed foramen ovale without hemodynamic changes have the possibility of self-healing and can be reviewed periodically. Congenital heart diseases such as simple atrial septal defect, ventricular septal defect, patent ductus arteriosus, and pulmonary stenosis have a better prognosis and can survive for a long time after correction, and most of them reach the quality of survival of normal population. For more complex congenital heart disease, the treatment plan will be decided by a specialist according to the degree of heart disease, and the diet and activities will be guided. Complex congenital heart disease requires early and aggressive treatment to achieve the physiological needs in terms of anatomical structure or cardiac function and to improve the quality of survival of the child.