The long-term use of active oil may have some hazards, mainly may cause local allergies, if used improperly can also aggravate the disease or cover up the disease, is not conducive to the diagnosis and treatment of the disease, affecting health. 1, allergies: the active oil itself has the role of activating blood, removing blood stasis, and promoting the absorption of blood stasis edema, which can improve local microcirculation. However, if used for a long time or in large quantities, it may stimulate the affected skin and produce allergic reactions, such as itching, redness, swelling, rash and other symptoms, and may even lead to local skin breakdown, resulting in increased pain and other conditions; 2, aggravate the condition: long-term use of active oil may lead to an imbalance in local circulation and metabolism, and long-term use of the drug will damage the skin microvascular structure, which is not conducive to regulating local metabolism, and will cause the deposition of metabolic waste And aggravate the inflammation, making the symptoms more obvious. In addition, for patients with local skin damage, if still used, it will stimulate the injury site, aggravate the pain and skin damage, and may also cause infection; 3, mask the condition: for some patients with bone and joint inflammation or soft tissue chronic injury, long-term use of active oil can control the symptoms to a certain extent, but can not completely reverse the pathological process, and can not delay the progress of degeneration . However, the reduction of symptoms can easily lead patients to believe that their condition is effectively controlled, thus delaying treatment and worsening their condition. In addition, patients who have changes in their condition, such as a local tendency to bleed, should stop using active oil to avoid aggravating their condition. The use of active oil needs to grasp the indications, pay attention to the contraindications, under the guidance of the doctor according to the condition of reasonable use of drugs to ensure the effectiveness of treatment as well as safety.