There are more causes of ulcers at the male corona, so the medication that needs to be applied needs to be based on the cause of the disease. Bacterial infection caused by the person to give erythromycin ointment and other antibacterial drugs; fungal infection caused by the person to apply ketoconazole cream and other antifungal drugs; syphilis caused by the ulcers can be used externally erythromycin ointment, etc.; genital herpes can be used externally acyclovir cream and other antiviral drugs. 1. Bacterial infection: mostly seen in patients with prolonged prepuce, circumcision, in addition to the presence of broken coronary groove, is also easy to lead to bacterial invasion, and then appeared in the coronary groove ulceration. Need to use iodophor or new cleaner and other disinfectant disinfection, local application of mupirocin ointment and other antibacterial drugs anti-infection treatment. 2. Fungal infections: the more common for Candida albicans infection, the coronary groove can also appear ulcerated, in the local disinfection can be used topical ketoconazole cream and other antifungal drugs treatment. 3. syphilis: a sexually transmitted disease caused by syphilis spirochete infection, patients can also appear in the coronary groove of the ulcers, in the use of penicillin antibacterial treatment at the same time, the local can also be thoroughly disinfected after applying erythromycin ointment and other antibacterial drugs. 4. Genital herpes: caused by herpes simplex virus infection, the beginning of the papules or blisters, and then can be broken to form ulcers. The treatment can be topical acyclovir cream and other antiviral drugs for treatment. It is recommended that the patient complete the auxiliary examination to clarify the cause of the disease, the professional physician for the cause of the corresponding treatment, the drug has side effects and contraindications, so need to be used under the guidance of a professional physician.