Nausea and vomiting on the second day of a hangover can be relieved by dietary modification, hot compresses on the upper abdomen, oral medication, acupoint stimulation, etc. 1. Dietary adjustments: Nausea and vomiting on the second day of a hangover may be caused by alcohol stimulating the gastric mucosa and weakening the gastrointestinal tract. You can adjust your diet and eat some warm and easy-to-digest food, such as rice porridge, noodles, egg custard, etc., to relieve the discomfort. 2. Hot compresses on the upper abdomen: Alcohol stimulates the gastric mucosa leading to spasms in the smooth muscle tissue of the stomach, and nausea and nausea can also occur. You can use a warm towel or a warm water bag to apply hot compresses to the upper abdomen to promote local blood circulation, reduce stomach spasms and relieve discomfort. 3. Oral medication: Alcohol stimulates the gastric mucosa, resulting in gastric mucosal damage, nausea and vomiting symptoms will occur. You can take drugs to inhibit gastric acid secretion, such as: omeprazole, pantoprazole and so on. You can also take drugs to protect the gastric mucosa, such as aluminum sulfate, magnesium aluminum carbonate and so on to reduce the damage of the gastric mucosa. You can also take drugs to promote gastrointestinal power, accelerate gastrointestinal peristalsis, relieve discomfort, such as domperidone, mosapride, etc.. 4. Acupuncture point stimulation: You can stimulate the acupuncture points that promote gastrointestinal peristalsis to reduce discomfort. For example, massaging acupoints such as foot-sanli, gastric epigastric and Guanyuan can enhance the function of the gastrointestinal tract and relieve the symptoms of nausea and vomiting. The above medications must be taken under the guidance of a clinician to avoid uncomfortable symptoms.