Patients with vesiculitis without blood sperm are usually given medication for 7 days, and if blood sperm is present in severe cases, it can be taken for 2 weeks to 3 weeks, and if it continues to show no improvement, they should go to a specialized hospital for further examination. Patients with vesiculitis are usually accompanied by generalized fever, chills, ejaculatory pain, lower abdominal and perineal discomfort. Some patients with mild symptoms can be offered to improve their lifestyle habits and exercise to relieve mild vesiculitis. If the patient’s symptoms are more obvious, levofloxacin can be used for anti-infection treatment. Usually taking levofloxacin for about a week can relieve the symptoms. Some patients with severe hematospermia may need to take the medication for a longer period of time, which may take about 2 weeks to 3 weeks. Patients with vesiculitis should seek medical attention as soon as possible, follow the doctor’s instructions to choose the appropriate treatment, and the medication should be applied under the guidance of the doctor.